The ID Now influenza A & B 2 assay has incorporated significant changes to both the amplification reaction and the analytical software compared to the original Alere i influenza A/B assay. LP36662-2 Influenza virus A & B Influenza virus from the family The BinaxNOW Influenza A & B test kit is an in vitro immunochromatographic assay for the qualitative detection of influenza A and B Careers. Allows for rapid te. " 2014 Nov;52(11):3992-5. doi: 10.1128/JCM.01639-14. SKU: FITEXTRAXXL. The ID NOW Influenza A & B 2 assay delivers molecular flu results in 13 minutes or less on our unique ID NOW platform; making it significantly faster than other molecular methods and more accurate than conventional rapid tests. The ID NOW Influenza A & B 2 assay delivers molecular flu results in 13 minutes or less on our unique ID Accessibility This book explores the status of paper-based diagnostic solutions, or Microfluidics 2.0. Prevention and treatment information (HHS). This is done in the context of recommended global TB strategies and targets endorsed by WHO?s Member States and broader development goals set by the United Nations (UN). Features. The PPA was 93.8% for influenza A and 94.1% for influenza B, and NPA was 100% for influenza A and influenza B virus. Alere i Influenza A & B 2 is a second-generation rapid molecular assay, which delivers lab accurate results in less time, with the ability to report a positive result in as little as 5 Influenza A Rapid Test Kit Market Analysis and Insights: The Global Influenza A Rapid Test The PPA was 93.8% for influenza A and 94.1% for influenza B, and NPA was 100% for influenza A and influenza B virus. This milestone greatly expands the availability of molecular testing to a This book provides researchers with widely used techniques for the study of virology, focusing on molecular biology and imaging to encourage mechanistic investigation of virus-host interactions. The Alere i influenza A&B test had an overall sensitivity and specificity of 93.8% and 62.5% for influenza A, respectively, and of 91.8% and 53.6% for influenza B, respectively. How could a rapid molecular result optimize patient care in your department? Found inside Page 23A study of 545 specimens (85% collected from children) found the Alere i Influenza A&B assay to be 99.3% sensitive and 98.1% specific for influenza A, and 97.6% sensitive and 100% specific for influenza B, compared with viral culture Alere i Strep A received Watanabe Y, Oikawa R, Suzuki T, Funabashi H, Asai D, Hatori Y, Takemura H, Yamamoto H, Itoh F. J Clin Lab Anal. Impact of a 24/7 Rapid Molecular Assay for Influenza Detection on the Prescription of Oseltamivir. Evaluation of the Alere I influenza A&B nucleic acid amplification test by use of respiratory specimens collected in viral transport medium. Youngs J, Marshall B, Farragher M, Whitney L, Glass S, Pope C, Planche T, Riley P, Carrington D. J Hosp Infect. The Alere i molecular platform was initially cleared for marketing by the FDA for the detection and differentiation of influenza A and B virus in June 2014. Comparison against culture Flu B 98.4% 99.4% PPA: Positive Percentage Agreement NPA: Negative Percentage Agreement Nasal Swab Direct or Product Name prduct Cde Sample Types in Viral Transport Media (VTM), - Nasopharyngeal Swab in VTM Alere i Influenza A & B 24 Test Kit 425-000 Time to Result <15 minutes Alere i *Prices are pre-tax. Rapid and accurate diagnosis of influenza is important for infection control, as well as for patient management. eCollection 2020 Aug. Jacquier H, Pan de Ponfilly G, Chauvin A, Amarsy R, Benmansour H, Hoang-Nguyen DT, Lecorch E, Mesnil C, Mougari F, Munier AL, Salmona M, Berot B, Le Goff J, Cambau E. Open Forum Infect Dis. Alere i Influenza A&B Test WAIVED 24/Bx Alere-i 425-024 Alere i Influenza A&B Test WAIVED Alere-i 425-024 425-024 Influenza A&B Test Disclaimer, National Library of Medicine J Clin Microbiol. Analyst. In total, 360 VTM specimens were selected for Alere i Influenza A&B testing: 40 influenza virus A H1N1-2009 (influenza virus A-1), 40 influenza virus A H3N2 (influenza virus A-3), 37 influenza virus A "equivocal" or "no subtype detected" (influenza virus A-u), 41 influenza virus B, and 202 influenza virus-negative specimens, as initially determined by the FilmArray RP assay. 2020 Aug 25;7(9):ofaa374. Epub 2021 Apr 7. Comparison of the Alere I and BD Veritor in the detection of Influenza A and B viruses. A systematic review of rapid diagnostic tests for influenza: considerations for the community pharmacist. Epub 2014 Dec 10. Bookshelf The performance characteristics of two commercially available rapid tests for influenza, the BD Veritor System for Flu A+B (BD) and the Alere BinaxNOW influenza A&B card (BN), were evaluated using 200 frozen clinical specimens collected from January 2011 to June 2012 from pediatric patients. The Alere i Influenza A&B assay described in this study is a novel isothermal-amplification-based integrated system for detection and differentiation of influenza virus A and influenza virus B. This study aimed to evaluate the impact of implementing rapid point-of-care testing (POCT) with the Alere i Influenza A & B in an emergency department (ED) during an influenza epidemic. From descriptions of the opportunities that POCT can provide to the limitations that clinicians must be cautioned about, this book provides an overview of the many aspects that challenge those who choose to implement POCT. This report presents the recommendations of a WHO Expert Committee commissioned to coordinate activities leading to the adoption of international recommendations for the production and control of vaccines and other biological substances and Unlike polymerase chain Added to this is the annual death toll of 250,000 to 500,000 people worldwide with a further 3 to 4 million people suffering severe illness. These statistics make influenza an extremely important pathogen. The Alere Reader will be initially available for use with the BinaxNOW Influenza A & B Card 2, with other lateral flow applications and assays to follow. As of January 2017, the company had a market capitalization of $3.47 billion with an enterprise value of $5.9 billion. Shares of Alere Inc. (), a global provider of point-of-care rapid diagnostic and health information solutions, spiked nearly 2.6% yesterday after the U.S. Food and Drug Administration (:FDA) approved its i Influenza A & B test. (B) Mechanism of product formation. We evaluated the clinical performance of the Alere i RSV assay in a pediatric point-of-care setting during winter season 2016 / 2017. PMC Found inside Page 1741The Liat Influenza A/B is performed in a closed system, provides results within 20 minutes, and demonstrates a 99.2% sensitivity compared to previously existing molecular methods.44 The Alere i Influenza A&B is a similar molecular test doi: 10.1093/ofid/ofaa374. Alere i Influenza A Influenza B Positive Negative Positive Negative BD Veritor Positive 13 1 7 0 Point-of-care testing for influenza in a university emergency department: A prospective study. 2021 Jan;107:35-39. doi: 10.1016/j.jhin.2020.09.035. 8600 Rockville Pike Diagnostic accuracy of the real-time PCR cobas. The Egilmezer E, Walker GJ, Bakthavathsalam P, Peterson JR, Gooding JJ, Rawlinson W, Stelzer-Braid S. Rev Med Virol. J Am Pharm Assoc (2003). The Alere i Influenza A & B 2 assay performed on the Alere i Instrument is a rapid molecular in vitro diagnostic test utilizing an isothermal nucleic acid amplification technology for the qualitative detection and discrimination of influenza A and B viral Alere i Influenza A & B is a rapid (less than 15 minutes), instrument-based isothermal test for the qualitative detection and differentiation of influenza A and influenza B from nasal swabs and nasal or nasopharyngeal swabs eluted in viral transport media. This third edition covers not only the most recent updates and advances, but details newly invented omic techniques, such as next generation sequencing. Incontinence Briefs: FitRight Extra Cloth-Like Adult Incontinence Briefs, Size 2XL, for Waist Size 60"-69". Respiratory syncytial virus (RSV) is the most important cause of severe acute respiratory tract infection in young children. J Clin Microbiol. Conclusions: The Alere i Influenza A&B isothermal nucleic acid amplification test is an ideal point-of-care test for influenza detection in children and adults due to its high sensitivity and The aim of this study was to compare Alere i Influenza A & B with an in-house real-time PCR for influenza virus detection in prospectively recruited patients presenting with flu symptoms during the 20112012 influenza season in Barcelona, Spain. Other Molecular Systems Accurate Performance A new level of confidence in test sensitivity a'b Judgement1,2 Rapid Antigen6 90 100% l~0% 10 [20 [30 [40 [50 l~66 [70 [80 a. When compared to viral culture, the new Alere test showed performance The Alere i Influenza A & B POCT reduced the length of stay in ED, the hospitalization rates, and the number of additional diagnostic tests compared with standard of care testing. Of the five genera in the family, only influenza A virus (IAV), Cleaved complexes are regenerated (3b), while products 1 and 2 can anneal to T1 and T2, respectively (4b), resulting in bidirectional extension and creating duplexes that generate the opposite product upon cleavage. This book is a printed edition of the Special Issue "Control of Communicable Diseases in Human and in Animal Populations: 70th Anniversary Year of the Birth of Professor Rick Speare (2 August 1947 5 June 2016)" that was published in 2016 Nov;54(11):2763-2766. doi: 10.1128/JCM.01586-16. Found inside Page 604Furthermore, monitoring of respiratory specimens in aggregate can identify when influenza is highly active. X X 65770 99100 BD Veritor System for Flu A+B (Becton- Dickinson) X X 70940 99100 BinaxNOW Flu A and Flu B (Alere) X X J Clin Virol. (A) Mechanism of NEAR amplification duplex formation. This volume provides an overview of molecular biology tools for pathogen detection and characterization. Despite similar rates in the prescription of antibiotics and antiviral therapies, the proportion of patients who were referred for additional tests was significantly lower in the POCT cohort (78.1% versus 62.1%, P=0.003, and 80.5% versus 63.6%, P=0.01, respectively). Would you like email updates of new search results? Alere i Influenza A & B Molecular. A single sample can be used to run both the QuickVue Influenza A+B Test and QuickVue RSV10 Test. Performance characteristics for influenza A and B were established during February through March 2011 when influenza viruses A/California/7/2009 (2009 H1N1), A/Perth/16/2009 (H3N2), and B/Brisbane/60/2008 * Alere receives FDA clearance for Alere I Influenza A & B 2 rapid molecular test * Alere Inc says will shortly submit an application for CLIA waiver of Alere i See this image and copyright information in PMC. Li-Kim-Moy J, Dastouri F, Rashid H, Khandaker G, Kesson A, McCaskill M, Wood N, Jones C, Zurynski Y, Macartney K, Elliott EJ, Booy R. J Paediatr Child Health. Alere i Influenza A & B delivers molecular flu results in less than 15 minutes on our unique Alere i platform; making it significantly faster than other molecular methods and more accurate than The ID Now (Abbott) influenza A & B 2 assay, formerly the Alere i influenza A/B 2 assay, is the latest improved version of the Alere i influenza A/B assay. Alere Inc., a leading global provider of point-of-care rapid diagnostic and health information solutions, today announced the availability in Europe of the Alere i Alere i Influenza A & B is the first-ever molecular test to receive a CLIA (Clinical Laboratory Improvement Amendments) waiver, which allows for The molecular test is the first-of-its-kind designed to detect and differentiate between two most common types of flu virus influenza A and B in It is intended to aid in the rapid differential diagnosis of influenza A and B viral infections. NguyenVan JC, Gerlier C, Pilmis B, Mizrahi A, Pan de Ponfilly G, Khaterchi A, Enouf V, Ganansia O, Le Monnier A. J Clin Virol. Ann Emerg Med. 2021All rights reserved The AccuBioTech SA Scientific Alere Coris BioConcept Quidel BD . Evaluation of a new point-of-care quantitative reverse transcription polymerase chain test for detecting severe acute respiratory syndrome coronavirus 2. The Alere" i Influenza A & B assay, performed on the Alere" i Instrument, is a rapid molecular in vitro diagnostic test utilizing an isothermal nucleic acid amplification technology for the qualitative detection and discrimination of influenza A and B viral RNA in nasal swabs from patients with signs and symptoms of respiratory infection. In minutes. Systematic review of the impact of point-of-care testing for influenza on the outcomes of patients with acute respiratory tract infection. (5a) Nicking enzyme binds and nicks (indicated by scissors). Prospective evaluation of ID NOW COVID-19 assay used as point-of-care test in an emergency department. Found inside Page 254influenza B antigens in nasopharyngeal or nasal speci- mens are available at most hospital-based laboratories and An A/Singapore/INFIMH-16-0019/2016 (H3N2)-like A new point-of-care influenza test (Alere i Influenza A and influenza B (6a) polymerase synthesizes off the cleaved 3 OH along T1, displacing the remaining target complement, and the final extended double-stranded complex is termed the NEAR amplification duplex. Alere i Influenza A & B 2 is a second-generation rapid molecular assay, which delivers lab accurate results in less time, with the ability to Subsequent sections of the report provide information on the current status proposed development and establishment of international reference materials in the areas of: antibiotics; blood products and related substances; cellular and gene (3a) A second T2 binds to the same target and is extended, displacing the first T2. 48509-4 Influenza virus A and B RNA [Identifier] in Specimen by NAA with probe detection Active Part Description. Epub 2012 Jul 27. The total elapsed time was, MeSH The Alere i Influenza A & B test revolutionizes rapid flu testing by providing highly accurate, molecular results in less than 15 minutes on the user-friendly Alere i platform. MeSH Methods: Direct nasal swabs were prospectively collected following the physical examination of patients aged >18years who presented to the ED of a tertiary hospital in In general, the Alere i Influenza A&B provided good sensitivity, although the assay did show poorer sensitivity with samples determined to have low influenza virus A titers by Prodesse ProFlu+ PCR (a mean real-time PCR threshold cycle [CT] value of 31.9 2.0), which included the majority of the samples called influenza virus A "equivocal" or "no subtype detected" by a single BioFire FilmArray RP test. Alere BinaxNOW Influenza A+B Waived (22/BX) 626296 159769 Alere Influenza A+B CLIA Waived (10/BX) 626298 140183 Alere Influenza A+B Dipstick (25/BX) 802651 268051 BD BBL Influenza A+B CLIA Waived Veritor (30/EA) 785953 264810 BD BBL Influenza A+B Veritor (30/EA) 826356 292451 Flu Testing Item No. Unable to load your collection due to an error, Unable to load your delegates due to an error. Conclusions: IMPLEMENTATION DATE: April 6, 2015. Margulis M, Erster O, Roth S, Mandelboim M, Danielli A. J Mol Diagn. Comparison against RT-PCR or viral culture b. This site needs JavaScript to work properly. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates. 2021 Sep 23;76(Suppl 3):iii28-iii32. Epub 2017 Jul 26. Found insideXpert FlusPSV is a PCR test and Alere" i is a nuclear acid amplification test. in Nguyen Van JC, Camlna F, Dahoun M, et al. Prospective evaluation of the Alere i Influenza A&B nucleic acid amplification versus Xpert FlusPSV. Safiabadi Tali SH, LeBlanc JJ, Sadiq Z, Oyewunmi OD, Camargo C, Nikpour B, Armanfard N, Sagan SM, Jahanshahi-Anbuhi S. Clin Microbiol Rev. The integrated, rapid, and simple characteristics of the Alere i Influenza A&B assay make it a potential candidate for point-of-care testing, with a test turnaround time of less than 15 min. Copyright 2017 Elsevier Inc. All rights reserved. AccessGUDID - Alere i Influenza A & B Control Swab Kit (10811877010811)- Control Swabs intended for use only with the Alere i Inuenza A & B product. This easy-to-use format and rapid results allow for point-of-care testing where it can provide information to assist with treatment and patient Direct Comparison of Alere i and cobas Liat Influenza A and B Tests for Rapid Detection of Influenza Virus Infection. Alere i Influenza A & B 2 is a second-generation rapid molecular assay, which delivers lab accurate results in less time, with the ability to report a positive result in as little as 5 Epub 2021 Sep 14. Alere i Influenza A&B is an isothermal nucleic acid amplification-based integrated system for detection and differentiation of influenza virus A and influenza virus B. J Clin Microbiol. The Alere i Influenza A & B test is the first and only molecular test to detect and differentiate influenza A Commercial Influenza Diagnostic Test Discrepant Results Reporting Tool. Alere i Influenza A & B vs. Culture1 Alere i demonstrates impressive sensitivity for the detection of both influenza A and B in clinical respiratory specimens obtained from children and adults. Epub 2016 Aug 31. The ID NOW Influenza A & B 2 assay delivers molecular flu results in 13 Clinicians often have to make immediate treatment decisions based only on signs and symptoms due to poor access to sensitive, rapid diagnostic tests and long turnaround times for laboratory PCR results. (4a) The recognition region of T1 binds to its complement in the released strand and is extended to the 5 end, creating a double-stranded nicking enzyme recognition site. Current state of commercial point-of-care nucleic acid tests for infectious diseases. Found inside Page 247Influenza Viruses Alere I Influenza A&B Assay The Alere i Influenza A&B assay (Alere, Waltham, MA) is a new, rapid molecular assay for identification and differentiation of influenza virus subtypes A and B from clinical specimens. Hinson JS, Rothman RE, Carroll K, Mostafa HH, Ghobadi K, Smith A, Martinez D, Shaw-Saliba K, Klein E, Levin S. J Hosp Infect. Found inside Page 761 and detection platform(s)d Extraction Platforms Targetse Specimen types approvedf Method(s)g References Alere i NAT Flu A/B Alere i Instrument Included FluA, FluB NS Isothermal amplification, Fluorescence detection [11, 12, 35, 91, DESCRIPTION. This is done in the context of recommended global TB strategies and targets endorsed by WHO's Member States, broader development goals set by the United Nations (UN) and targets set in the political declaration at the first UN high-level RESULTS: The sensitivity and specificity of the Alere i Influenza A&B assay for detection of influenza A virus was 80.0% and 98.1%, and for influenza B virus 45.2% and 98.2%, respectively. Alere TM Influenza A & B Test The AlereTM Influenza A & B Test provides a simple, rapid method as an aid in the differential diagnosis of influenza A & B using nasal swab specimens. 2021 Oct;35(10):e23992. If microorganisms are found, these are identified and susceptibility profiles, when indicated, are determined. Found insideComparison of the Alere i to the BD Veritor in the rapid detection of Influenza A and B viruses G. J. Berry1, O. O. Oladipo1, D. Wittnebert2, P. Mann1, M. Loeffelholz1, J. R. Petersen1. 1UTMB, Galveston, TX, 2Memorial Medical Center Found inside Page 799Table 47.1 (continued) Manufacturer Test name bioMrieux Alere Scarborough, Inc. bioMrieux/BioFire Cepheid Focus Alere I influenza A and B Pneumonia FilmArray respiratory panel Pneumonia Xpert flu/RSV Pneumonia Xpert flu The primary endpoint was patient time in the ED. EFFECTIVE DATE: April 1, 2015 *Unless otherwise Topics discussed in this volume include, but are not limited to: whole genome sequencing in critically ill children, bioinformatics in clinical genomic sequencing, comprehensive monitoring of patients with chronic myeloid leukemia, genetic the Alere i Influenza A & B Test {Direct Nasal swab only}. The Fastest Rapid Molecular Flu Test. Tools and Techniques for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)/COVID-19 Detection. Alere i Influenza A & B 2 is a second-generation rapid molecular assay, which delivers lab accurate results in less time, with the ability to report a positive result in as little as 5 minutes. Plus a new name. Copyright 2014, American Society for Microbiology. Prevention and treatment information (HHS). (1a and 2a) The recognition region of T2 binds to the complementary target region and is extended by polymerase along the target. Alere i Influenza A&B is an isothermal nucleic acid amplification-based integrated system for detection and differentiation of influenza virus A and influenza virus B. FDA has granted Alere, Waltham, Mass, a Clinical Laboratory Improvement Amendments (CLIA) waiver for the Alere i Influenza A & B test, the only molecular test to detect Bethesda, MD 20894, Help Here's a practical resource on the diagnosis of viral pathogens. Epub 2014 Sep 10. Alere i is a CLIA waived test that easy to use. Table 1. 41116144. How accurate are rapid influenza diagnostic tests? 2021 May 12;34(3):e00228-20. This reformulated test card is Performance of the molecular Alere I influenza A&B test compared to that of the xpert flu A/B assay. This Recurring Update Notification applies to Chapter 16, section 70.8 of the IOM. Alere NMP22 BladderChek Test Alere 86386QW BTA stat Test (for home use) Bion Diagnostic Sciences 86294QW LifeScan Status BTA Polymedco, Inc 86294QW Maritech BladderCheck Maritech, Inc. 86386QW BUN (Blood Urea Nitrogen) Abaxis Piccolo Blood Chemistry Analyzer (Chem 6 and 13 Panels, CMP, BMP, Metlyte 8, Renal) Abaxis, Inc. 84520QW NEAR mechanism. The performance characteristics of two commercially available rapid tests for influenza, the BD Veritor System for Flu A+B (BD) and the Alere BinaxNOW influenza A&B card (BN), were All Rights Reserved. Alere 425-080 - ALERE I FLU A&B CONTROL. Rapid influenza diagnostic test at triage can decrease emergency department length of stay. A significantly higher proportion of patients received a positive diagnosis in the POCT cohort compared with the pre-POCT cohort (31% versus 5.3%, P<0.01). Perlitz B, Slagman A, Hitzek J, Riedlinger D, Mckel M. Influenza Other Respir Viruses. "The Alere BinaxNOW Influenza A & B Card 2 test with the Alere Reader, improves what is already a leading rapid testing solution for influenza diagnosis in two key ways: by eliminating operator subjectivity and by connecting test results with information management systems," said Avi Pelossof, Alere Global President of Infectious Disease. The company was formerly known as Inverness Medical Innovations, Inc. and changed its name to Unable to load your collection due to an error, Unable to load your delegates due to an error. The Sofia Influenza A+B FIA may be used with Sofia or Sofia 2. Point of care testing for infectious disease: ownership and quality. 2015 Feb;53(2):706-9. doi: 10.1128/JCM.02783-14. 2021 Apr 21;146(8):2449-2462. doi: 10.1039/d0an01988g. Alere i Influenza A & B Molecular. eCollection 2020 Sep. Utility of early influenza diagnosis through point-of-care testing in children presenting to an emergency department. This is done in the context of recommended global TB strategies and associated targets, and broader development goals. This site needs JavaScript to work properly. Alere i Influenza A & B is the first molecular diagnostic test that delivers actionable, lab-accurate results in less than 15 minutes on a user When Alere i influenza A & B was compared to R-mix cell culture using direct nasal swabs from both adults and children, with testing performed at seven POC sites, the sensitivities after the resolution of discrepant results was 99.3% for influenza A virus and 96.7% for influenza B, with specificities of 98.1% and 100%, respectively . Study objective: In this study, we Standard Facial Tissues. (1b and 2b) Nicking enzymes bind to both nicking enzyme recognition sites on the NEAR duplex; cleavage and strand displacement amplification at both sites creates two complexes, each consisting of a duplex stability region, a nicking enzyme recognition region, and a single-stranded target.
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