OBJECTIVES: In 2003, the US Food and Drug Administration issued warnings about hyperglycemia and diabetes with second-generation antipsychotics (SGAs); guidelines have recommended metabolic screening since 2004. Peter Treitler, MSW, Madeline H. Bono, PsyM, Brendan Saloner, PhD, Stephen Crystal, PhD, Large-Scale New Jersey Prison Releases During COVID-19: Experiences of Released Prisoners with Substance Use Disorders, Zhaoyong Huang, Yuzhu Chen, Weiwen Zhou, Xiaopeng Li, Qiulan Qin, Yunqing Fei, Xinqi Dong, Fang Yu, Factors affecting independence in basic and instrumental activities of daily living have been established in older adults, but not centenarians. Not having to inject, less risk of low blood sugars and few side effects, the benefits of use are easy to see. Medical devices play a vital role in diagnosing, treating, and preventing diseases and are an integral part of the health-care system. Is nondiabetic hyperglycemia a risk factor for cardiovascular disease? Purpose: This paper describes the core elements of U.S. nurse practice acts and provides an update of Lavin, Meyer, and Carlson (1999) Review of the Use of Nursing Diagnosis in U.S. Nurse Practice Acts. Delayed or incomplete follow-up after abnormal screening results may compromise the effectiveness of breast cancer screening programs, particularly in medically underserved and minority populations. We determined the response to Truvada-based first-line combination antiretroviral therapy (cART) in HIV/HBV-coinfected verus HIV-monoinfected patients in Botswana. Nucleoside analogue reverse transcriptase inhibitors are an integral component of combination antiretroviral treatment regimens. It's a novel way to lower blood sugars, lose weight and maybe live longer. Lancet 2010;375:2215-22. Even though we are waiting for the completion of studies such as TAME (Metformin as a Tool to Target Aging) to find out whether metformin can really delay the onset of age related diseases the evidence is building and metformin can indeed be seen to have many beneficial effects other than regulating blood glucose levels. However, no study has yet evaluated the expression of MMP-8, known as neutrophil collagenase, the enzyme that preferentially degrades type I collagen, because granulocytes do not localize in plaques. Lai, Vincent W.P. Diabetes Care 2011;34:2508-14. Background: Short-term mortality rates among patients with HIV receiving antiretroviral therapy (ART) in sub-Saharan Africa are higher than those recorded in high-income countries, but systematic long-term comparisons have not been made because of the scarcity of available data. N Engl J Med 2009;361:1736-47. It's important that before starting any medication, that you and your doctor discuss all the pros and cons. Data were from the 2003 NJ FamilyCare Family Health Survey (n=416 families). Data from the Population Study of ChInese , Weiyu Mao, Bei Wu, Iris Chi, Wei Yang, Xinqi Dong, Suzanne Meeks, Background and Objectives: Despite an increasing, yet still limited amount of research on social determinants of oral health, the influences of neighborhood characteristics, Man Guo, Meredith Stensland, Mengting Li, Xinqi Dong, Objectives: This study aims to identify (a) different types of parent-child relations among Chinese older immigrants, (b) predictors of each relation type, and (c) the most optimal , Background: Given the importance of ethnic culture in family caregiving and recent Chinese immigrant population growth, this study explored effects of multiple filial , In reply to Dr. Yoshikawas comments, we acknowledge that the PINE/PIETY studies have limited generalizability that may not apply to other ethnic , Man Guo, Meredith Stensland, Mengting Li, Todd Beck, Xinqi Dong, Suzanne Meeks, Background and Objectives: The family fundamentally underpins the immigration and acculturation processes. It is important to note that metformin should not be used by individuals without diabetes for the prevention of dementia as there is no evidence to support this use. Check out community events and happenings at Rutgers Institute for Health! It was only in the last century that the discovery of antibiotics freed us from many of the dreaded diseases of the past , Zeeshan Ahmed, Saman Zeeshan, Dinesh Mendhe, XinQi Dong, Introduction: Since the beginning of scientific discoveries, it has been critically central to understand the cause of disease, pain, and senescence.1 Over the centuries, quests for the answers have led us to take giant leaps. BACKGROUND: Permanent supportive housing (PSH) programs have the potential to improve health and reduce Medicaid expenditures for beneficiaries experiencing homelessness. The Ageless Generation is an engaging work that causes us to rethink our ideas of age and ability in the modern world. The rapid growth of antipsychotic medication use among publicly insured children in the early and mid-2000s spurred new state efforts to monitor and improve prescription behavior. Contact: Britta Galling, Alexandra Roldn, Ren E. Nielsen, Jimmi Nielsen, Tobias Gerhard, Maren Carbon, Brendon Stubbs, Davy Vancampfort, Marc De Hert, Mark Olfson, Kai G. Kahl, Andres Martin, Jeff J. Guo, Hsien Yuan Lane, Fung Chang Sung, Chun Hui Liao, Celso Arango, Christoph U. Correll. Method: Data were drawn from the baseline of the Shanghai Aging Study. Findings will have statewide and national importance toward promoting a culture of health. Effective treatment of chronic illness requires active engagement of patients in managing their own conditions. Optimal glycemic control is fundamental to the management of diabetes. All content on guidelines.diabetes.ca, CPG Apps and in our online store remains exactly the same. Methods. Prior research has shown that receipt of LtOT in accordance with clinical practice guidelines has the potential to mitigate these outcomes. Methods: Data were from the Population Study of Chinese Elderly (PINE) in which 2,713 participants (aged 60 and older) received in-home interviews at both the baseline and 2-year follow-up. BackgroundDispensing data from Medicare Part D standalone prescription drug plans are now available, but characteristics of enrollees with heart failure have not been well described. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Factors that predict psychiatric hospitalization rather than outpatient care are (1) public or private insurance coverage versus no insurance; (2) previous hospitalization; (3) psychiatric diagnosis of affective or psychotic disorders versus conduct disorders, adjustment disorders, drug and alcohol abuse, and other disorders; and (4) age, with adolescents more likely to be hospitalized than children. June Gruber, Mitchell J. Prinstein, Lee Anna Clark, Jonathan Rottenberg, Jonathan S. Abramowitz, Anne Marie Albano, Amelia Aldao, Jessica L. Borelli, Tammy Chung, Joanne Davila, Erika E. Forbes, Dylan G. Gee, Gordon C.Nagayama Hall, Lauren S. Hallion, Stephen P. Hinshaw, Stefan G. Hofmann, Steven D. Hollon, Jutta Joormann, Alan E. Kazdin, Daniel N. Klein, Annette M. La Greca, Robert W. Levenson, Angus W. MacDonald, Dean McKay, Katie A. McLaughlin, Jane Mendle, Adam Bryant Miller, Enrique W. Neblett, Matthew Nock, Bunmi O. Olatunji, Jacqueline B. The mean duration of diabetes was 12 years and the A1C levels achieved in the standard and intensive therapy groups were 8.4% and 6.9%, respectively. Alcohol use increases non-adherence to antiretroviral therapy (ART) among persons living with HIV (PLWH). But most existing research on acculturation , Minority populations are increasing rapidly in the United States, with the Asians the fastest growing population. OBJECTIVE: We examined whether having a psychiatric disorder among HIV-infected individuals is associated with differential rates of discontinuation of HAART and whether the number of mental health visits impact these rates. Xinqi Dong, Ruijia Chen, Terry Fulmer, Melissa A. Simon. Higher glycemic targets are also appropriate for functionally dependent adults of any age or individuals with limited life expectancy and little likelihood of benefit from intensive therapy. In most people with type 1 or type 2 diabetes, an A1C 7.0% should be targeted to reduce the risk of microvascular [Grade A, Level 1A, In people with type 2 diabetes, an A1C 6.5% may be targeted to reduce the risk of CKD [Grade A, Level 1A. More recently, in a 2007-2008 survey of 1,190 colleges, it was found that nearly one-third of students participated in service (Campus Compact, 2009). An efficient infrastructure to support multinational pharmacoepidemiologic studies is critical to this effort. Of the various types of diabetes, type 2 diabetes is increasing in prevalence due to obesity, aging, sedentarism, and other factors. This book presents a novel approach to preventing and treating type 2 diabetes. Researchers today are trying to determine what is causing the disparities in hospitalizations and deaths of Black Americans during COVID-19. Roberto Lewis-Fernndez, Marcela Horvitz-Lennon, Carlos Blanco, Peter Guarnaccia, Zhun Cao, Margarita Alegra. Access scientifically rigorous and efficient survey and data research services for investigators. Repeat self-harm per 1,000 personyears and suicide rates per 100,000 person-years (based on cause of death information from the National Death Index) were determined. It is thought that this affect is a result of minimising DNA damage by decreasing reactive oxygen in our cells, effectively acting as a powerful antioxidant in preventing tumour growth. Xinqi Dong, Stephanie M. Bergren, Melissa A. Simon. Participants Dual-eligible individuals aged 65 and older who initiated antipsychotic treatment in a NH (N = 75,445). As one of the leading causes of death around the world, suicide is a global public health threat. These trialsthe DCCT in type 1 diabetes (11), the Kumamoto trial (12) and the UKPDS (1,13) in type 2 diabetesconfirmed that improved glycemic control significantly reduced the risk of microvascular complications, but had no significant effect on CV outcomes. Objectives To explore differences in the incidence of postoperative complications between three racial and ethnic groups (white, black, Hispanic) before and after taking into account potentially confounding patient and hospital characteristics. This book explains how telemedicine can offer solutions capable of improving the care and survival rates of cancer patients and can also help patients to live a normal life in spite of their condition. Lancet 1998;352:854-65. The I-MACST characterizes the treatment practices of on entire facility with little demand on staff time. Calles-Escandon J, Lovato LC, Simons-Morton DG, et al. Found inside Page 173TABLE 1 | Continued Study Patient no/follow up Patient history Comparison Parameter HR (95% CI) Tecos (Green et al. for a potential anti-aging effect of metformin may be expected from the Targeting Aging with Metformin (TAME) trial, Susan Forman, Nancy Fagley, Brian Chu, James Walkup. IMPORTANCE: Antiretroviral therapy (ART) has converted human immunodeficiency virus (HIV) infection into a chronic condition, and patients now undergo a variety of surgical procedures, but current surgical outcomes are inadequately characterized. Olga Jarrin Montaner, Linda Flynn, Eileen T. Lake, Linda H. Aiken. Objective To compare confounding adjustment by high-dimensional propensity scores (hdPSs) and historically developed high-dimensional disease risk scores (hdDRSs) in three comparative study examples of newly marketed medications: (1) dabigatran vs. warfarin on major hemorrhage; (2) on death; and (3) cyclooxygenase-2 inhibitors vs. nonselective nonsteroidal anti-inflammatory drugs on gastrointestinal bleeds. Importance: The incidence of Clostridium difficile infection has increased among children. Arch Intern Med 2004;164:2147-55. Impact of fasting and postprandial glycemia on overall glycemic control in type 2 diabetes Importance of postprandial glycemia to achieve target HbA1c levels. Jessica J. Wyse, Jonathan L. Robbins, Kathleen A. McGinnis, E. Jennifer Edelman, Adam J. Gordon, Ajay Manhapra, David A. Fiellin, Brent A. Moore, P. Todd Korthuis, Julie R. Gaither, Kirsha Gordon, Melissa Skanderson, Declan T. Barry, Stephen Crystal, Amy Justice, Kevin L. Kraemer. This book offers a broad-ranging assessment of current efforts of the molecular, cellular, hormonal, nutritional and lifestyle strategies being tested and applied by biogerontologists in the search for effective means of intervention, However, little is known about recent trends in the use of these procedures and the associated outcomes among older patients. Founded by eminent medical sociologist David Mechanic PhD in 1985. Sample Data: The data are from a 1986 nationally representative sample surveyed by the National Institute of Mental Health. FLAT-SUGAR Trial Investigators. A new medication for the treatment of obesity has been approved by the FDA, and it received significant media attention in the months leading up to its approval. Hiraku Kumamaru, Sebastian Schneeweiss, Robert J. Glynn, Soko Setoguchi Iwata, Joshua J. Gagne. Context: Although physicians communication skills have been found to be related to clinical outcomes and patient satisfaction, teaching of communication skills has not been fully integrated into many medical school curricula or adequately evaluated with large-scale controlled trials. Learn about current COVID-19 research and community resources, a list of New Jersey testing sites and more. In the Chicago Health and Aging Project (N = 8,932), 238 participants had reported elder abuse. Secondary disease prevention is an important component of survivorship care that has not been previously evaluated. It is important to have this medication at mealtimes to minimize these effects. Design Retrospective cohort study. We identified a cohort of pregnancies ending in live birth within the 2000-2007 Medicaid Analytic eXtract (MAX). Purpose: Newly approved novel drugs in Europe receive a black triangle label to promote pharmacovigilance. Examination of patient and provider experiences of the transition from curative to palliative care promises valuable insights about establishing and maintaining trust as the goals of care shift and about addressing a broad spectrum of patient needs. We analysed the effect of the implementation of Botswanas national ART programme, known as Masa, from 2002 to 2010. Xinqi Dong, Ruijia Chen, Bei Wu, Ning Jackie Zhang, Ada Chan Yuk Sim Mui, Iris Chi. The outcome of interest was oral ulceration, defined by the presence diagnoses of stomatitis and mucositis, aphthous-like ulceration and oral burns, or dispensing of stomatological corticosteroids included triamcinolone, dexamethasone, hydrocortisone, and prednisolone. The provision of antiretroviral drugs for the prevention of mother-to-child HIV transmission has been rising sharply in low- and middle-income countries. The current paper applies the SEM to data collected at multiple levels, representing different layers of the SEM, and examines the unique and relative contribution of each layer to childrens weight status. Linkages between registries and administrative data may provide a valuable resource for comparative effectiveness research. Using data from the Veterans Aging Cohort Study, we consider minority status and sexual orientation jointly to characterize and compare these factors. Therefore, this study examined the association between depression treatment and healthcare expenditures among elderly with depression and incident cancer. T. Scott Stroup, Tobias Gerhard, Stephen Crystal, Cecilia Huang, Zhiqiang Tan, Melanie M. Wall, Chacku Mathai, Mark Olfson. Tobias Gerhard, K. Huybrechts, M. Olfson, S. Schneeweiss, W. V. Bobo, P. M. Doraiswamy, D. P. Devanand, J. Examining predictors of alcohol use among adolescent girls is increasingly important to enhance prevention efforts, given that the gender gap in alcohol use is steadily closing. Stephen Crystal, Dennis G. Shea, Adriana M. Reyes. Diabetes in Older Adults: A Growing Population With Special Challenges. Background: For the pending National Claims Database in Japan, researchers will not have access to death information in the enrollment files. Almut G. Winterstein, Rene Soria-Saucedo, Tobias Gerhard, Christoph U. Correll, Mark Olfson. Bethan McDonald, Sikhulile Moyo, Lesego Gabaitiri, Simani Gaseitsiwe, Hermann Bussmann, John R. Koethe, Rosemary Musonda, Joseph Makhema, Vladimir Novitsky, Richard Marlink, C. William Wester, Max Essex. James Walkup, Ayse Akincigil, Scott Bilder, Nancy Scotto Rosato, Stephen Crystal. Subsequent observational data from long-term follow up after termination of randomization periods of both the DCCT and UKPDS cohorts showed a persistence of significant microvascular benefits and also demonstrated an emergence of beneficial effect on CV outcomes attributed to intensive glycemic control. Parental eligibility was higher in households without a full-time employedparent(oddsratio [OR]=5.50; 95% confidence interval [CI]=2.72, 11.14) and lower among single parents (OR=0.38; 95% CI=0.23, 0.61). Background: Warfarin use and associated outcomes in patients with heart failure and atrial fibrillation and a cardiovascular implantable electronic device have not been described previously. Diabetologia 2006;49:442-51. Disease risk scores (DRSs) developed in historical comparator drug users before the new drug entered the market may improve adjustment. Edward Chia Cheng Lai, Patrick Ryan, Yinghong Zhang, Martijn Schuemie, N. Chantelle Hardy, Yukari Kamijima, Shinya Kimura, Kiyoshi Kubota, Kenneth K.C. Report Accessibility Barrier / Provide Feedback form. Yiwei Chen, Yisheng Peng, Minzhi Ye, Ling Xu, Xinqi Dong. Background: Despite demonstrated efficacy in randomized trials, aldosterone antagonist therapy is not used in many eligible patients with heart failure. Approved in 2002 for attention-deficit/hyperactivity disorder treatment, the selective noradrenalin-reuptake-inhibitor atomoxetine was initially investigated for the treatment of depression. Here are the side effects and what to do about them. Beginning in 2020, this study will be the largest of its kind in New Jersey to date. Context: Hospice care is traditionally used for patients with advanced cancer, but it is increasingly considered for patients with end-stage heart failure. We compared changes in alanine and aspartate aminotransferases (ALT and AST) and total bilirubin (TB) stratified by HIV status. Older men are less likely than older women to receive depression treatment. Data were drawn from the Population Study of Chinese Elderly including 3159 Chinese American older adults aged 60 and above in the greater Chicago area. IMPORTANCE Although adults with schizophrenia have a significantly increased risk of premature mortality, sample size limitations of previous research have hindered the identification of the underlying causes. In addition, results show that the I-MACST differentiates between services in child and adolescent inpatient units and that it detects differences in services that reflect changes in the organization of one hospital. New insulin glargine 300 U/ml compared with glargine 100 U/ml in insulin-naive people with type 2 diabetes on oral glucose-lowering drugs: A randomized controlled trial (EDITION 3). The participation of racial and ethnicminorities and underserved populations in clinical trials is a critical link between scientific innovation and improvements in health care delivery and health outcomes. Learn more about our legacy, our mission, and our vision for the future of population health research in a new video. Medicine owes a debt of gratitude to the authors of this work. --Doodys Review Service For nearly three decades, the goal of Essentials of Clinical Geriatrics has remained unchanged: to help clinicians do a better job of caring for As these studies have only examined cancer risk retrospectively, large clinical trials are now underway such as the Targeting Aging with Metformin (TAME) in the USA which is collecting data over a 5-year period not only looking at the occurrence of cancers but We compared the influence of substance abuse with that of other comorbidities (e.g., anxiety, HIV) among people with mood disorder (N=129524) to explore risk factors for psychiatric hospitalization and early readmission within 3 months of discharge.
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